HYPERTENSIVE NEPHROPATHY

Hepatocyte nuclear factor 1 and hypertensive nephropathy.

Hypertension in spontaneously hypertensive rat (SHR) is associated with renal redox stress, and we hypothesized that nephropathy arises in SHR-A3 from altered capacity to mitigate redox stress compared with nephropathy-resistant SHR lines. We measured renal expression of redox genes in distinct lines of the spontaneously hypertensive rat (SHR-A3, SHR-B2, SHR-C) and the normotensive Wistar-Kyoto...

Proteinuria in Hypertensive Nephropathy: A Review

Hypertension defined as a systolic blood pressure of ≥140 and a diastolic blood pressure ≥90 is an extremely prevalent condition; and it is responsible for significant mortality and morbidity. NHANES data from 2005-2006 found that nearly 30% of adult US population has HTN; and nearly 8% of the population has undiagnosed HTN. HBP mortality in 2008 was 61,005. Any mentioned mortality in 2008 was ...

Diabetic and hypertensive nephropathy in India.

Rapamycin-induced hypokalaemic nephropathy in a middle-aged hypertensive male.

Del Castillo V. Hypomelanosis of Ito: diagnostic criteria and report of 41 cases. Pediatric Dermatol 1992; 9: 1–10 2. David TJ. Hypomelanosis of Ito: a neurocutaneous syndrome. Arch Dis Child 1981; 56: 798–800 3. Coward RJM, Risdon RA, Bingham C, Hattersley AT, Woolf AS. Kidney disease in hypomelanosis of Ito. Nephrol Dial Transplant 2001; 16: 1267–1269 4. Chevalier C, Colon S, Faraj G, Bouvier...

The lymphocyte migration inhibitor FTY720 attenuates experimental hypertensive nephropathy.

The lymphocyte migration inhibitor FTY720 attenuates experimental hypertensive nephropathy. Infiltration with lymphocytes is found in both immune and nonimmune chronic kidney diseases. In a rat model of immune-initiated progressive glomerulosclerosis, selective inhibition of lymphocyte infiltration by FTY720 showed significant beneficial effects on renal fibrosis. To test whether this translate...